李芳红,教授,博士生导师,国家特聘专家,广东省珠江人才计划创新创业团队第一核心成员,现为广东工业大学百人计划特聘教授。1990年毕业于中国医科大学预防医学系。1995年取得硕士学位并留校中山大学卫生学院任教。1998年,选派到新加坡国立大学接受WHO项目培训。2000到2006年间,在美国波士顿和匹兹堡大学医学院从事研究助理工作。2006年获得美国医学博士证书,同年进入美国Saint Barnabas 医学中心的病理系,完成了四年的严格的组织病理和临床病理的住院医生训练。2010-2011年,在美国约翰霍普金斯大学(Johns Hopkins)医学院病理系从事妇科病理专科工作。李教授多年来从事病理,毒理,骨代谢,肥胖、糖尿病和癌症的分子机制和药物开发研究以及病理诊断的标准化研究。以第一作者的身份,在一系列高影响因子的专业杂志上相继发表了多篇文章,如Nature Medicine, American Journal of Surgical Pathology, American Journal of Physiology, Journal of Biological Chemistry, Journal of Bone and Mineral Research,International Journal of Surgical Pathology 等。
研究领域
1. 基因工程改造的微生物在肿瘤治疗中的应用;
2. 多不饱和脂肪酸代谢对糖尿病和肥胖的影响机制及药物研发;
3. 脱细胞异种生物材料在临床中的应用;
4. 肿瘤分子病理和个性化病理诊断以及代谢性相关妇科疾病研究;
近期论文
1. Bi X, Li F, Liu S, Jin Y, Zhang X, Yang T, Dai Y, Li X, Zhao AZ*,ω-3 polyunsaturated fatty acids ameliorate type 1 diabetes and autoimmunity.,J Clin Invest,2017.5.1,127(5):1757-1771.
2. Cheng, Lixian,Shi, Hui,Jin, Yan,Li, Xiaoxi,Pan, Jinshun,Lai, Yimei,Lin, Yan,Jin, Ya,Roy, Gaurab,Zhao, Allan*,Li, Fanghong*,Adiponect in Deficiency Leads to Female Subfertility and Ovarian Dysfunctions in Mice.,Endocrinology,2016.12.01, 57(12): 4875~4887.
3. Li, Jie,Wei, Dong,McCrory, Mark A,Szalai, Alexander J,Yang, Gangyi,Li, Ling,Li, Fanghong*,Zhao, Allan Z *,Human C-reactive protein impedes entry of leptin into the CNS and attenuates its physiological actions in the CNS.,Biochem J,2016.05.1,473(9): 1215~1224.
4. Zhu, Yan,Yu, Meining,Ma, Luyao,Xu, Hai,Li, Fanghong Rose*,Choriocarcinoma-associated pulmonary thromboembolism and pulmonary hypertension: a case report.,J Biomed Res,2016.05.01,30(3): 243~247.
5. Pan J,Cheng L,Bi X,Zhang X, Liu S,Bai X,Li F,Zhao AZ*, Elevation of ω-3 Polyunsaturated Fatty Acids Attenuates PTEN-deficiency Induced Endometrial Cancer Development through Regulation of COX-2 and PGE2 Production., Sci Rep,2015.10.15,5:14958.
6. Zeng, Fangxin,Shi, Jinyu,Long, Yang,Tian, Haoming,Li,Xiaoxi,Zhao, Allan Z,Li, Rose Fanghong*,Chen, Tao *,Adiponectin and Endometrial Cancer: A Systematic Review and Meta-Analysis.,Cellular Physiology and Biochemistry.,2015.01.01,36(4): 1670~1678.
7. Chen, Ke(#) ,Li, Fanghong(#),Li, Ji,Cai, Hongbo,Strom, Steven,Bisello, Alessandro,Kelley, David E,Friedman-Einat, Miriam,Skibinski, Gregory A,McCrory, Mark A,Szalai, Alexander J,Zhao, Allan Z,Induction of leptin resistance through direct interaction of C-reactive protein with leptin.,Nat Med,2006.04.01,12(4): 425~432.
8. Li, Jie(#),Li, Fanghong R(#),Wei, Dong,Jia, Wei,Kang, Jing X,Stefanovic-Racic, Maja,Dai, Yifan,Zhao, Allan Z*,Endogenous omega-3 polyunsaturated fatty acid production confers resistance to obesity, dyslipidemia, and diabetes in mice.,Molecular Endocrinology.,2014.08.01,28(8): 1316~1328.
9. Li, Rose Fanghong(#),Gupta, Mamta,McCluggage, W Glenn,Ronnett, Brigitte M,Embryonal rhabdomyosarcoma (botryoid type) of the uterine corpus and cervix in adult women: report of a case series and review of the literature.,Am J Surg Pathol,2013.3.01,37(3): 344~355.
10. Li, Fanghong(#),Chung, Hoyeon,Reddy, Sakamuri V,Lu, Ganwei,Kurihara, Noriyoshi,Zhao, Allan Z*,Roodman, G David,Annexin II stimulates RANKL expression through MAPK.,J Bone Miner Res,2005.07.01,20(7): 1161~1167.
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