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侯雪丹 副教授

发布日期:2019-01-10    作者:     来源:     点击:

侯雪丹 Hou Xuedan 副教授    

 

所属学院:生物医药学院

导师类别:硕士生导师

职务: 

科研方向:1.生物资源绿色加工与转化:废弃生物资源的高值转化与利用;2. 生物催化与生物转化:天然产物(药物)的酶法修饰和微生物转化合成。

Email houxd@gdut.edu.cn;  QQ: 84778387

招生学院:生物医药学院

个人简述:

侯雪丹,博士,广东工业大学生物医药学院硕士生导师,广东工业大学青年百人计划引进人才,Bioresource Technology, Energy Conversion and Management, ACS Sustainable Chemistry & EngineeringJournal of Molecular Liquids多个国际期刊审稿人。近年来主要围绕生物技术能源转化、天然产物的生物催化与生物转化等前沿领域开展一系列研究,在绿色溶剂体系的理性设计及其在生物能源和生物催化领域的应用方面积累了丰富的研究经验。迄今,以第一作者身份在生物工程顶级期刊Biotechnology and Bioengineering上连续发表3篇文章,在Green ChemistryBioresource Technology等国际著名学术刊物上已发表十多篇学术论文,单篇最高SCI论文引用231次,总计SCI论文引用超过850次。

学科领域

科学学位:制药工程

专业学位:材料与化工(生物医药方向)

教育背景

09/2009-09/2013 华南理工大学生物科学与工程学院 生物化工 工学博士

09/2006-07/2009 华南理工大学生物科学与工程学院 发酵工程 工学硕士

09/2002-07/2006 武汉轻工大学生物与制药工程系 生物工程 工学学士

工作经历

2019/01 至今     广东工业大学生物医药学院 生物工程系,副教授

2018.11-2019.11  伦敦帝国理工学院 化学工程系,访问研究员 

2013/09-2018/12  广东工业大学轻工化工学院  生物工程系,讲师

主要荣誉

2014年获得华南理工大学优秀博士学位论文

20142017年获得广东工业大学校先进科技工作者

2012年获得优秀博士研究生国家奖学金。

科研项目

1. 国家自然科学基金面上项目: 22078068,基于低共熔溶剂的双相溶剂体系中玉米芯组分定向解聚-产物原位分离耦合的协同机制及预处理强化机理, 2021/01-2024/12, 63, 在研,主持

2.国家自然科学基金青年基金,21406038基于半纤维素选择性萃取的深度共熔溶剂预处理木质纤维素生物质的研究2015/01-2017/1225万元,结题,主持

3.广东省科技计划项目,2016A010105021,发酵蔬菜中降解亚硝酸盐乳酸菌的分离及应用开发,2016/05-2019/05,30万元,在研,参与

4.广州市科技计划项目-珠江新星专项,2012J2200011,含DES介质中β-糖苷酶催化二糖核苷合成的研究,2012/07-2015/0630万元,已结题,参与

5.横向项目——19HK0051,料添加剂生产菌株复壮及生产工艺改良,2019/02-2020/05,结题,主持

发表论文

1. Kai-Peng Lin, Guo-Jian Feng, Fu-Long Pu, Hou, Xue-Dan*, Shi-Lin Cao, Enhancing the Thermostability of Papain by Immobilizing on Deep Eutectic Solvents-Treated Chitosan With Optimal Microporous Structure and Catalytic Microenvironment. Frontiers in Bioengineering and Biotechnology, 2020, 8.

2. Zi-Jian Huang , Guo-Jian Feng, Kai-Peng Lina , Fu-Long Pu, Yan-Ming Tana , Wei-Chien Tu, Ya-Li Han, Xue-Dan Hou*, Hong-Mei Zhang, Yi Zhang.  Significant boost in xylose yield and enhanced economic value with one-pot process using deep eutectic solvent for the pretreatment and saccharification of rice straw. Industrial Crops and Products, 2020, 152:112515.

3. Xue-Dan Hou*, Ao-Lin Li, Kai-Peng Lin, Yuan-Yuan Wang, Zhi-Yin Kuang, Shi-Lin Cao. Insight into the structure-function relationships of deep eutectic solvents during rice straw pretreatment. Bioresource Technology, 2018, 249:261-267.

4. Xue-Dan Hou*, Kai-Peng Lin, Ao-Lin Li, Lu-Min Yang, Ming-Hui Fu. Effect of constituents molar ratios of deep eutectic solvents on rice straw fractionation efficiency and the micro-mechanism investigation. Industrial Crops and Products, 2018, 120:322-329.

5. Ao-Lin Li, Xue-Dan Hou*,Kai-Peng Lin, Xuan Zhang, and Ming-Hui Fu. Rice straw pretreatment using deep eutectic solvents with different constituents molar ratios: Biomass fractionation, polysaccharides enzymatic digestion and solvent reuse. Journal of Bioscience and Bioengineering, 2018, 126(3): 346-354.

6. Xue-Dan Hou*, Guo-Jian Feng, Mei Ye, Chao-Mei Huang, Yi Zhang*. Significantly enhanced enzymatic hydrolysis of rice straw via a high performance two-stage deep eutectic solvents synergistic pretreatment. Bioresource Technology, 2017, 238: 139-146.

7. Xuedan Hou, Jie Xu, Ning Li *, Minhua Zong *. Effect of anion structures on cholinium ionic liquids pretreatment of rice straw and the subsequent enzymatic hydrolysis, Biotechnology and Bioengineering, 2015, 112(1): 65-73.

8. Xuedan Hou, Ning Li*, Minhua Zong*. Renewable bio ionic liquids-water mixtures-mediated selective removal of lignin from rice straw: visualization of changes in composition and cell wall structure; Biotechnology and Bioengineering, 2013, 110 (7), 1895-1902.

9. Xuedan Hou, Ning Li*, Minhua Zong*. Significantly enhancing enzymatic saccharification of rice straw after pretreatment using renewable ionic liquid-water mixtures; Bioresource Technology, 2013, 136: 469-474.

10. Xuedan Hou, Ning Li*, Minhua Zong*. Facile and simple pretreatment of sugarcane bagasse without size reduction using renewable ionic liquids-water mixturesACS Sustainable Chemistry and Engineering, 2013, 1(5): 519- 526.

11. Xuedan Hou, Thomas J. Smith, Ning Li*, Minhua Zong*. Novel Renewable Ionic Liquids as Highly Effective Solvents for Pretreatment of Rice Straw Biomass by Selective Removal of Lignin, Biotechnology and Bioengineering, 2012, 109(10):2484-2493.

12. Qiuping Liu, Xuedan Hou (co- first author), Ning Li, Minhua Zong*, Ionic liquids from renewable biomaterials: synthesis, characterization and application in the pretreatment of biomass, Green Chemistry, 2012, 14 (2),304-307.

13. Xuedan Hou, QiuPing Liu, Thomas J. Smith, NingLi, Minhua Zong*. Evaluation of toxicity and biodegradability of cholinium amino acids ionic liquids, PLoS ONE , 2013, 8(3), e59145.

14. W Li; H Wu; BG Liu; Xue-Dan Hou; DJ Wan; WY Lou ; J Zhao. Highly efficient and regioselective synthesis of dihydromyricetinesters by immobilized lipase, Journal of Biotechnology, 2015, 199: 31-37.

15. Xue-Dan Hou, Wen-Yong Lou*, Li-Qiang Yan, Min-Hua Zong*. Influences of ionic liquids on catalytic performances of papain. Chemical Journal of Chinese Universities, 2012, 33: 1245-1251.

16. Xue-Dan Hou, Yi Zhang, Huan Liu, Ning Li, Min-Hua Zong. Enzymatic Synthesis of 5'-Palmitate of 5-Fluorouridine. Chinese Journal of Catalysis, 2011, 32: 1733-1738.

17. Shi-Lin. Cao, W. M. Gu, W. D. Ou-Yang, D. C. Chen, B. Y. Yang, L. H. Lai, Y. J. Liu, J. Zhu, W. J. Chen, Z. Q. Gai, Xue-Dan Hou, Y. Z. Ma, and Y. X. An, Preparation, Characterization and Application of Rod-Like Chitin Nanocrystal by Using p-Toluenesulfonic Acid/Choline Chloride Deep Eutectic Solvent as a Hydrolytic Media, Carbohydrate Polymers, 2019, 213: 304-310.

18. 黄梓健 杨露敏 林凯鹏 冯国坚 张永昊 蒲福龙 古榕榕 侯雪丹,不同类型深度共熔溶剂预处理的甘蔗渣酶解效率差异,现代食品科技,2020,06, 60-67.

19. 叶梅,黄超梅,林凯鹏,冯国坚,侯雪丹. 经胆碱氨基酸水溶液预处理的水稻秸秆中残余木质素对多糖酶水解抑制作用研究, 现代食品科技,2017:33(5)71-76.

专利

1.李宁,侯雪丹,宗敏华,[胆碱][氨基酸]离子液体预处理提高水稻秸秆酶解效率的方法,2014.07.16,中国,ZL201210004741.8

2.李宁,宗敏华,侯雪丹,一种利用可再生离子液体水溶液预处理木质纤维素的方法,2014.05.07,中国,ZL201210540656.3

3.一种利用乳/盐酸胍提取半纤维素以提高水稻秸秆中纤维素酶解效率的绿色方法,2019.2.21,中国发明专利,已授权,授权号:CN106480128B

4.一种利用两种深度共熔溶剂分步预处理以提高水稻秸秆中纤维素酶解效率的绿色方法,2016.10.31,中国发明专利,申请号: CN201610929252.1

5.一种利用深度共熔溶剂去除衣服霉斑的绿色方法,2019.6.14,中国发明专利,已授权,授权号:CN106480128B

6.一种用于提取霉菌胞内果糖基转移酶的深度共熔溶剂及其制备方法和应用,2019-04-16,中国发明专利,申请号:CN201910305797.9

7.一种利用绿色溶剂提取霉菌胞内多糖的方法,2019-08-28,中国发明专利,申请号:CN201910803274.7

 

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